Old Age Issue Description Repaired with regeneration?
1 Cataracts Poor vision leads to disadvantage on perception checks and ranged attack rolls No
Anything over 15 feet away is blurry and it is hard to distinguish friends from foes
2 Withered arm or hand You can no longer hold anything with 2 hands. You can only hold a single object at a time Yes
3 Withered leg or foot Movement rate is halved, you cannot dash, you must use a cane or crutch to move. Yes
Disadvantage on dexterity checks for balance
4 Degenerative disease Cancer or something very bad is eating up your body. Whenever taking an action in combat you must No
make a DC 15 Con save. On failure you lose your action, and can't use reactions until your next turn
5 Massive wrinkles Your skin has lost elasticity and is horribly wrinkled. Disadvantage on persuasion checks -2 to Cha No
6 Deafness the eardrums are not damaged, just old and worn out 75% hearing loss means that you can't hear enemies coming at you.  No
Disadvantage on perception checks. Normal sounds that are over 50 feet away can't be heard at all.
7 Breathing disease Lung disease has permanently reduced the effectiveness of the lungs and makes it hard to breathe. The exertion of combat No
makes you fatigued, after 3 rounds of fighting, you must make a con save DC 15 or you have to rest 2 rounds before taking
any more strenuous actions, like fighting, running, etc.
8 Heart disease Heart disease has permanently redused the effectiveness of your heart and makes it hard to be active. The exertion of combat No
puts a strain on your heart and after 3 rounds of fighting you must make a con save DC 15 or pass out. If not attended to, you will 
not wake up without medical attention
9 Joint disease Cartilage and bone loss make it painful to exert yourself. After 3 rounds of strenuous activity, your pain becomes so bad that  Yes
you have to make a con save DC 15 or be forced to rest for 2 rounds
10 Mental weakness Alzheimers or dementia makes your memory poor. Bouts of clarity are inturrupted by periods of complete loss. You don't  No
remember any skill classes, such as spell casting, fighting, etc. Once every hour you must make a wisdom check DC15 to avoid having
a spell of forgetfullness, that will last an hour.